USE OF A SYNTHETIC PROTEASE INHIBITOR FOR THE TREATMENT OF L-ASPARAGINASE-INDUCED ACUTE-PANCREATITIS COMPLICATED BY DISSEMINATED INTRAVASCULAR COAGULATION

被引：23

作者：

MURAKAWA, M

OKAMURA, T

SHIBUYA, T

HARADA, M

OTSUKA, T

NIHO, Y

机构：

[1] First Department of Internal Medicine, Faculty of Medicine, Kyushu University, Fukuoka, 812, 3-1-1 Maidashi, Higashi-ku

来源：

ANNALS OF HEMATOLOGY | 1992年 / 64卷 / 05期

关键词：

L-ASPARAGINASE; DRUG-INDUCED PANCREATITIS; PROTEASE INHIBITORS; CONSUMPTION COAGULOPATHY; DISSEMINATED INTRAVASCULAR COAGULATION;

D O I：

10.1007/BF01738305

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In two patients receiving L-asparaginase therapy, severe acute pancreatitis complicated by disseminated intravascular coagulation (DIC) developed. In both cases it was successfully treated with continuous infusion of a synthetic protease inhibitor, nafamostat mesilate. In this report, we briefly discuss the clinical efficacy of the synthetic protease inhibitor in treating such cases.

引用

页码：249 / 252

页数：4

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