PRENATAL NICOTINE EXPOSURE INCREASED SUSCEPTIBILITY TO ELECTROCONVULSIVE SHOCK (ECS) IN ADULT-RATS

被引：8

作者：

BRITOS, SA

ORSINGHER, OA

机构：

[1] Departamento de Farmacología, Facultad de Ciencias Quimicas, Universidad Nacional de Córdoba Sucursal 16, 5016 Córdoba

来源：

NEUROTOXICOLOGY AND TERATOLOGY | 1991年 / 13卷 / 03期

关键词：

PRENATAL NICOTINE EXPOSURE; ELECTROCONVULSIVE SHOCK;

D O I：

10.1016/0892-0362(91)90072-5

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Female rats were treated during pregnancy (days 1-20) with nicotine (1 mg/kg SC, b.i.d.). When some aspects of maternal behavior and developmental parameters were recorded in mothers and pups, respectively, no changes were detected in the experimental group as compared with controls. However, adult offspring of nicotine-treated rats showed an increased susceptibility to ECS. These results demonstrate long-lasting deleterious effects induced by nicotine exposure during fetal life.

引用

页码：271 / 273

页数：3

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