VIRUS-INFECTIONS IN MICE WITH TARGETED GENE DISRUPTIONS

被引：36

作者：

DOHERTY, PC

机构：

[1] St. Jude Children's Research Hospital, Memphis

来源：

CURRENT OPINION IN IMMUNOLOGY | 1993年 / 5卷 / 04期

关键词：

D O I：

10.1016/0952-7915(93)90026-O

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The experimental dissection of the ways that the various cells and molecules of the immune system interact to promote virus clearance has been greatly facilitated by the availability of mice with targeted disruptions of key genes. New insights are emerging, and details of host resistance mechanisms that could only be inferred for the in vivo situation are now being clearly established.

引用

收藏

页码：479 / 483

页数：5

相关论文

共 33 条

[1] A SOLUBLE RECEPTOR FOR INTERLEUKIN-1-BETA ENCODED BY VACCINIA VIRUS - A NOVEL MECHANISM OF VIRUS MODULATION OF THE HOST RESPONSE TO INFECTION [J].

ALCAMI, A ;

SMITH, GL .

CELL, 1992, 71 (01) :153-167

[2] TRANSGENIC MICE LACKING CLASS-I MAJOR HISTOCOMPATIBILITY COMPLEX-RESTRICTED T-CELLS HAVE DELAYED VIRAL CLEARANCE AND INCREASED MORTALITY AFTER INFLUENZA-VIRUS CHALLENGE [J].

BENDER, BS ;

CROGHAN, T ;

ZHANG, LP ;

SMALL, PA .

JOURNAL OF EXPERIMENTAL MEDICINE, 1992, 175 (04) :1143-1145

[3] DIFFERENT RULES GOVERN HELP FOR CYTOTOXIC T-CELLS AND B-CELLS [J].

BENNINK, JR ;

DOHERTY, PC .

NATURE, 1978, 276 (5690) :829-831

[4] INEFFICIENT POSITIVE SELECTION OF T-CELLS DIRECTED BY HEMATOPOIETIC-CELLS [J].

BIX, M ;

RAULET, D .

NATURE, 1992, 359 (6393) :330-333

[5] ACTIVATION OF CYTOKINE GENES IN T-CELLS DURING PRIMARY AND SECONDARY MURINE INFLUENZA PNEUMONIA [J].

CARDING, SR ;

ALLAN, W ;

MCMICKLE, A ;

DOHERTY, PC .

JOURNAL OF EXPERIMENTAL MEDICINE, 1993, 177 (02) :475-482

[6]

DOHERTY PC, 1992, ANNU REV IMMUNOL, V10, P123

[7]

DOHERTY PC, 1993, J NEUROIMMUNOL

[8] CLEARANCE OF INFLUENZA-VIRUS RESPIRATORY-INFECTION IN MICE LACKING CLASS-I MAJOR HISTOCOMPATIBILITY COMPLEX-RESTRICTED CD8+ T-CELLS [J].

EICHELBERGER, M ;

ALLAN, W ;

ZIJLSTRA, M ;

JAENISCH, R ;

DOHERTY, PC .

JOURNAL OF EXPERIMENTAL MEDICINE, 1991, 174 (04) :875-880

[9] THEILERS VIRUS-INFECTION OF BETA-2-MICROGLOBULIN-DEFICIENT MICE [J].

FIETTE, L ;

AUBERT, C ;

BRAHIC, M ;

ROSSI, CP .

JOURNAL OF VIROLOGY, 1993, 67 (01) :589-592

[10] CELL-SURFACE EXPRESSION OF H-2DB REQUIRES N-LINKED GLYCANS [J].

FRASER, JD ;

ALLEN, H ;

FLAVELL, RA ;

STROMINGER, JL .

IMMUNOGENETICS, 1987, 26 (1-2) :31-35

← 1 2 3 4 →