NOVEL H-1-BENZIMIDAZOL-4-OLS WITH POTENT 5-LIPOXYGENASE INHIBITORY ACTIVITY

被引：15

作者：

BUCKLE, DR ^{[1
]}

FOSTER, KA ^{[1
]}

TAYLOR, JF ^{[1
]}

TEDDER, JM ^{[1
]}

THODY, VE ^{[1
]}

WEBSTER, RAB ^{[1
]}

BERMUDEZ, J ^{[1
]}

MARKWELL, RE ^{[1
]}

SMITH, SA ^{[1
]}

机构：

[1] BEECHAM PHARMACEUT, DIV RES, MED RES CTR, HARLOW CM19 5AD, ESSEX, ENGLAND

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1987年 / 30卷 / 12期

关键词：

D O I：

10.1021/jm00395a007

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：2216 / 2221

页数：6

共 29 条

[1]

ACKERMAN N, 1980, J PHARMACOL EXP THER, V215, P588

[2]

ASHIDA Y, 1983, PROSTAGLANDINS, V26, P955, DOI 10.1016/0090-6980(83)90157-0

[3]

BANTLIN A, 1878, BER DTSCH CHEM GES, V11, P2104

[4] 1-PHENYL-3-PYRAZOLIDONE - INHIBITOR OF CYCLO-OXYGENASE AND LIPOXYGENASE PATHWAYS IN LUNG AND PLATELETS [J].

BLACKWELL, GJ ;

FLOWER, RJ .

PROSTAGLANDINS & OTHER LIPID MEDIATORS, 1978, 16 (03) :417-425

[5]

BLACKWELL GJ, 1978, BRIT J PHARMACOL, V63, pP360

[6] RATIONALLY DESIGNED, POTENT COMPETITIVE INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS [J].

COREY, EJ ;

CASHMAN, JR ;

KANTNER, SS ;

WRIGHT, SW .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1984, 106 (05) :1503-1504

[7] SHORT, STEREOCONTROLLED SYNTHESES OF IRREVERSIBLE EICOSANOID BIOSYNTHESIS INHIBITORS - 5,6-DEHYDROARACHIDONIC,8,9-DEHYDROARACHIDONIC, AND 11,12-DEHYDROARACHIDONIC ACID [J].

COREY, EJ ;

KANG, J .

TETRAHEDRON LETTERS, 1982, 23 (16) :1651-1654

[8]

CORNFORTH JW, 1957, HETEROCYCL COMPOUNDS, P418

[9]

DADSWORTH MF, 1927, J CHEM SOC, P580

[10]

FORDHUTCHINSON AW, 1980, NATURE, V286, P2646

← 1 2 3 →