SYNTHESIS OF OPTICALLY PURE (R)-2-HYDROXY ACIDS USING D-LACTATE DEHYDROGENASE

被引：25

作者：

KIM, MJ

KIM, JY

机构：

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1991年 / 05期

关键词：

D O I：

10.1039/c39910000326

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Several (R)-2-hydroxy acids have been prepared in high optical purities and good yields using D-lactate dehydrogenase (Staphylococcus epidermidis) as the catalyst.

引用

页码：326 / 327

页数：2

共 24 条

[1] ASYMMETRIC REDUCTION OF ALPHA-KETO ESTERS WITH POTASSIUM 9-O-(1,2-5,6-DI-O-ISOPROPYLIDENE-ALPHA-D-GLUCOFURANOSYL)-9-BORATABICYCLO[3.3.1]NONANE - CHIRAL SYNTHESIS OF ALPHA-HYDROXY ESTERS WITH OPTICAL PURITY APPROACHING 100-PERCENT EE
BROWN, HC
CHO, BT
PARK, WS
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1986, 51 (17) : 3396 - 3398
[2] REGENERATION OF NICOTINAMIDE COFACTORS FOR USE IN ORGANIC-SYNTHESIS
CHENAULT, HK
WHITESIDES, GM
[J]. APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, 1987, 14 (02) : 147 - 197
[3] NUCLEAR MAGNETIC-RESONANCE ENANTIOMER REAGENTS - CONFIGURATIONAL CORRELATIONS VIA NUCLEAR MAGNETIC-RESONANCE CHEMICAL-SHIFTS OF DIASTEREOMERIC MANDELATE, O-METHYLMANDELATE, AND ALPHA-METHOXY-ALPHA-TRIFLUOROMETHYLPHENYLACETATE (MTPA) ESTERS
DALE, JA
MOSHER, HS
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1973, 95 (02) : 512 - 519
[4] ASYMMETRIC OXYGENATION OF CHIRAL IMIDE ENOLATES - A GENERAL-APPROACH TO THE SYNTHESIS OF ENANTIOMERICALLY PURE ALPHA-HYDROXY CARBOXYLIC-ACID SYNTHONS
EVANS, DA
MORRISSEY, MM
DOROW, RL
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1985, 107 (14) : 4346 - 4348
[5] ACYCLIC TERTIARY AND QUATERNARY CARBON STEREOCONTROL VIA NEW ALDOL EQUIVALENT REACTIONS OF OPTICALLY-ACTIVE (E)-ENOL ETHERS
FAUNCE, JA
FRIEBE, TL
GRISSO, BA
LOSEY, EN
SABAT, M
MACKENZIE, PB
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1989, 111 (12) : 4508 - 4510
[6] HANESSIAN S, 1983, TOTAL SYNTHESIS NATU, pCH2
[7] HIGH STEREOSELECTIVITY IN LEWIS-ACID-CATALYZED AND UNCATALYZED DIELS-ALDER REACTIONS OF THE FUMARATE OF (S)-ETHYL LACTATE
HARTMANN, H
HADY, AFA
SARTOR, K
WEETMAN, J
HELMCHEN, G
[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1987, 26 (11): : 1143 - 1145
[8] Helmchen G, 1986, MODERN SYNTHETIC MET, V4, P261
[9] LABORATORY-SCALE ENZYMATIC CHEMICAL SYNTHESES OF D-L-BETA-CHLOROLACTIC AND L-BETA-CHLOROLACTIC ACID AND D-POTASSIUM AND L-POTASSIUM GLYCIDATE
HIRSCHBEIN, BL
WHITESIDES, GM
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1982, 104 (16) : 4458 - 4460
[10] L-LACTATE DEHYDROGENASE - SUBSTRATE-SPECIFICITY AND USE AS A CATALYST IN THE SYNTHESIS OF HOMOCHIRAL 2-HYDROXY ACIDS
KIM, MJ
WHITESIDES, GM
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1988, 110 (09) : 2959 - 2964

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