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CYSTEINE PROTEINASES OF PARASITIC PROTOZOA

被引：159
作者：
NORTH, MJ
MOTTRAM, JC
COOMBS, GH
机构：
[1] UNIV GLASGOW,INST GENET,WELLCOME UNIT MOLEC PARASITOL,GLASGOW G11 5JS,SCOTLAND
[2] UNIV GLASGOW,DEPT ZOOL,BIOCHEM PARASITOL LAB,GLASGOW G12 8QQ,SCOTLAND
来源：
PARASITOLOGY TODAY | 1990年 / 6卷 / 08期
关键词：
D O I：
10.1016/0169-4758(90)90189-B
中图分类号：
R38 [医学寄生虫学]; Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ; 100103 ;
摘要：
Proteinases are involved with many processes in living organisms. In recent years, there has been increasing interest in elucidating the functions the enzymes perform in parasites. These studies have revealed that one class of proteinases, the cysteine proteinases, predominates in many parasitic protozoa. In this article Mick North, Jeremy Mottram and Graham Coombs review what is known about the cysteine proteinases of parasitic protozoa and discuss the approaches being pursued in attempts to design antiparasite drugs based on inhibitors or substrates of these enzymes. © 1990.
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页码：270 / 275
页数：6
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