THE HUMAN IMMEDIATE-EARLY GENE BRF1 MAPS TO CHROMOSOME 14Q22-Q24

被引：14

作者：

MACLEAN, KN

SEE, CG

MCKAY, IA

BUSTIN, SA

机构：

[1] UNIV LONDON,LONDON HOSP,COLL MED,ACAD SURG UNIT,LONDON E1 1BB,ENGLAND

[2] UNIV LONDON,LONDON HOSP,COLL MED,DEPT EXPTL DERMATOL & MORBID ANAT,LONDON E1 1BB,ENGLAND

来源：

GENOMICS | 1995年 / 30卷 / 01期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1006/geno.1995.0014

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

BRF1 (Butyrate response factor 1) is a member of an immediate early gene family specifying putative nuclear transcription factors. A repeat motif incorporating two Cys and two His is highly conserved between family members identified from yeast, Drosophila, mouse, rat, and human. The chromosome localization of none of the human genes has been determined thus far. Using the polymerase chain reaction on a human-rodent hybrid panel, we have localized BRF1 to chromosome 14. This was confirmed by direct sequencing of the PCR fragment. Using fluorescence in situ hybridization, the chromosome localization of BRF1 was further determined as 14q22-q24. (C) 1995 Academic Press, Inc.

引用

页码：89 / 90

页数：2

共 15 条

[1] CODING SEQUENCE OF ERF-1, THE HUMAN HOMOLOG OF TIS11B/CMG1, MEMBERS OF THE TIS11 FAMILY OF EARLY RESPONSE GENES [J].