ELEVATED PLATELET INTRACELLULAR CALCIUM-CONCENTRATION IN BIPOLAR DEPRESSION

被引：97

作者：

DUBOVSKY, SL

LEE, C

CHRISTIANO, J

MURPHY, J

机构：

[1] CATHOLIC UNIV,COLL MED,DEPT PSYCHIAT,SEOUL,SOUTH KOREA

[2] UNIV COLORADO,SCH MED,DEPT MED,DENVER,CO 80262

[3] UNIV COLORADO,SCH MED,DEPT BIOMET & PREVENT MED,DENVER,CO 80262

来源：

BIOLOGICAL PSYCHIATRY | 1991年 / 29卷 / 05期

关键词：

D O I：

10.1016/0006-3223(91)90266-O

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Baseline and thrombin-stimulated free intracellular calcium concentrations in blood platelets were significantly higher in untreated depressed bipolar patients than in untreated unipolar depressed patients or controls. Platelet intracellular calcium ion concentrations in euthymic-treated bipolar patients were equivalent to control values, suggesting but not proving a state-dependent change in intracellular calcium ion dynamics in bipolar depression. Unipolar and some subsets of bipolar patients appear not to exhibit this change.

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收藏

页码：441 / 450

页数：10

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