STREPTOCOCCUS-PNEUMONIAE-INDUCED HEMOLYTIC-UREMIC SYNDROME - A CASE FOR EARLY DIAGNOSIS

被引:42
作者
ERICKSON, LC
SMITH, WS
BISWAS, AK
CAMARCA, MA
WAECKER, NJ
机构
[1] USN HOSP,DEPT PEDIAT,SAN DIEGO,CA 92134
[2] USN HOSP,DEPT PATHOL,SAN DIEGO,CA 92134
[3] USN HOSP,DEPT CLIN INVEST,SAN DIEGO,CA 92134
关键词
HEMOLYTIC UREMIC SYNDROME; STREPTOCOCCUS-PNEUMONIAE; PNEUMONIA;
D O I
10.1007/BF00865481
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Hemolytic uremic syndrome associated with infection by neuraminidase-producing Streptococcus pneumoniae usually presents with fulminant pneumonia and has a high mortality rate. Post-pneumococcal hemolytic uremic syndrome may occur earlier in life than classical hemolytic uremic syndrome. We describe an 18-month-old male with hemolytic uremic syndrome, S. pneumoniae pneumonia, and T-antigen activation characteristic of neuraminidase activity. We have summarized the features of this case and 11 previously reported children. As the use of blood products containing IgM may aggravate this disorder, early recognition of hemolytic uremic syndrome associated with S. pneumoniae neuraminidase production may lead to improved patient outcome through the judicious use of blood products.
引用
收藏
页码:211 / 213
页数:3
相关论文
共 12 条
  • [1] Fischer K., Poschmann A., Oster H., Hamolyse bei schwerer Pneumonie infolge Neuraminidasewirkung, Monatsschr Kinderheilk, 119, (1971)
  • [2] Kim Y.D., Prakash U., Weber G.F., Hargie M., Nature of human serum blood group T antibodies, Immunol Commun, 8, pp. 397-406, (1979)
  • [3] Novak R.W., Martin C.R., Hemolytic-uremic syndrome and T-cryptantigen exposure by neuraminidase-producing pneumococci: an emerging problem?, Pediatr Pathol, 1, pp. 409-413, (1983)
  • [4] Feld L.G., Springate J.E., Darragh R., Fildes R.D., Pneumococcal pneumonia and hemolytic uremic syndrome, Pediatr Infect Dis J, 6, pp. 693-695, (1987)
  • [5] Klein P.J., Bulla M., Newman R.A., Muller P., Uhlenbruck G., Schaefer H.E., Kruger G., Fisher R., Thomsen-Freidenreich antigen in haemolytic-uraemic syndrome, Lancet, 2, pp. 1024-1025, (1977)
  • [6] Martinot A., Hue V., Leclerc F., Chenaud M., Haemolytic-uraemic syndrome associated with Streptococcus pneumoniae meningitis, Eur J Pediatr, 148, pp. 648-649, (1989)
  • [7] Alon U., Adler S.P., Chan J.C.M., Hemolytic-uremic syndrome associated with Streptococcus pneumoniae: report of a case and review of the literature, Am J Dis Child, 138, pp. 496-499, (1984)
  • [8] Seger R., Joller P., Baerlocher K., Kenny A., Dulake C., Leumann E., Spierig M., Hitzig W.H., Hemolytic-uremic syndrome associated with neuraminidase-producing microorganisms: treatment by exchange transfusion, Helv Paediatr Acta, 35, pp. 359-367, (1980)
  • [9] McGraw M.E., Lendon M., Stevens R.F., Postlethwaite R.J., Taylor C.M., Haemolytic uraemic syndrome and the Thomsen Friedenreich antigen, Pediatr Nephrol, 3, pp. 135-139, (1989)
  • [10] Austrian R., Gold J., Pneumococcal bacteremia with especial reference to bacteremic pneumococcal pneumonia, Annals of Internal Medicine, 60, pp. 759-776, (1964)