CYTOKERATIN EXPRESSION IN CHONDROBLASTOMAS

被引：31

作者：

SEMMELINK, HJF

PRUSZCZYNSKI, M

TILBURG, AWV

SMEDTS, F

RAMAEKERS, FCS

机构：

[1] Department of Pathology, University Hospital Nijmegen

来源：

HISTOPATHOLOGY | 1990年 / 16卷 / 03期

关键词：

chondroblastomas; epithelial markers; immunohistochemistry;

D O I：

10.1111/j.1365-2559.1990.tb01112.x

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The present study is based on the histopathological and immunohistochemical examination of seven chondroblastomas, including one lung metastasis occurring 9 years after treatment. Chondroblastomas were shown to co‐express vimentin, S‐100 protein, neuron‐specific enolase, and the epithelial markers recognized by CAM 5.2, EMA and a polyclonal cytokeratin antibody. The cytokeratins present in the tumour cells of the lung metastasis were characterized as cytokeratins 8, 18, 19 and, to a lesser extent, cytokeratin 7. The results suggest aberrant cytokeratin expression in chrondroblastomas. Copyright © 1990, Wiley Blackwell. All rights reserved

引用

页码：257 / 263

页数：7

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