IMMUNOLOGICAL AND ENZYMATIC STUDIES OF ERYTHROCYTIC DELTA-AMINOLEVULINATE DEHYDRATASE - COMPARISON OF RESULTS OBTAINED IN NORMAL AND LEAD-EXPOSED SUBJECTS

被引：17

作者：

BOUDENE, C ^{[1
]}

DESPAUXPAGES, N ^{[1
]}

COMOY, E ^{[1
]}

BOHUON, C ^{[1
]}

机构：

[1] INST GUSTAVE ROUSSY HAUTES BRUYERES, UNITE BIOL CLIN & EXPTL, F-94800 VILLEJUIF, FRANCE

来源：

INTERNATIONAL ARCHIVES OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH | 1984年 / 55卷 / 01期

关键词：

D O I：

10.1007/BF00378071

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

The .delta.-aminolevulinate dehydratase (ALA.D) quantitative assay on a centrifugal fast analyzer showed that subjects whose blood Pb level varied between 30-75 .mu.g/100 ml (1.5-3.75 .mu.M/l) reacted to blood intoxication by synthesizing de novo an amount of enzyme correlating to blood Pb levels. At higher concentrations the reactional synthesis occurred rarely. The enzyme was constitutive, but also inductible as soon as its substrate accumulated; this last ability may have disappeared at high blood-Pb levels.

引用

页码：87 / 96

页数：10

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