EVALUATION OF A REGION-WIDE HEPATITIS-B VACCINATION PROGRAM IN DIALYSIS PATIENTS - EXPERIENCE IN AN ITALIAN REGION

被引：18

作者：

ALBERTONI, F

BATTILOMO, A

DINARDO, V

FRANCO, E

IPPOLITO, G

MARINUCCI, G

PERUCCI, CA

PETROSILLO, N

SOMMELLA, L

机构：

[1] REG EPIDEMIOL UNIT,ROME,ITALY

[2] BRACCIANO HOSP,ROME,ITALY

[3] RIETI HOSP,ROME,ITALY

[4] SPALLANZANI HOSP,ROME,ITALY

[5] UNIV ROME 2,ROME,ITALY

[6] S GIACOMO HOSP,ROME,ITALY

[7] FROSINONE HOSP,ROME,ITALY

[8] ROME CATHOLIC UNIV HOSP,ROME,ITALY

来源：

NEPHRON | 1991年 / 58卷 / 02期

关键词：

HEPATITIS-B; DIALYSIS; VACCINATION PROGRAM; REGIONAL EVALUATION;

D O I：

10.1159/000186411

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

In 1985-1986, 634 adult dialysis patients were tested prior to hepatitis B vaccination, representing 40% of the total patients in Latium, an Italian region. HBsAg and anti-HBs prevalences were 7.1 and 36.0%, respectively. Merck, Sharp & Dohme (MSD) and Pasteur plasma-derived vaccines were randomly allocated to the 44 dialysis units. An anti-HBs response greater-than-or-equal-to 10 IU/1 was elicited in 58.5% of 236 subjects tested at 6 months, 63.4% MSD and 52.4% Pasteur (p n.s.). The relatively low response to the vaccine in this high-risk group stresses the need to improve the efficacy of the vaccination and to maintain policies of environmental control.

引用

页码：180 / 183

页数：4

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