ILEOCOLONIC ANASTOMOSIS AFTER RIGHT HEMICOLECTOMY FOR CARCINOMA - STAPLED OR HAND-SEWN - A PROSPECTIVE, MULTICENTER, RANDOMIZED TRIAL

被引:78
作者
KRACHT, M [1 ]
HAY, JM [1 ]
FAGNIEZ, PL [1 ]
FINGERHUT, A [1 ]
机构
[1] ARC,8 AVE PEULIERS,F-92270 BOIS COLOMBES,FRANCE
关键词
D O I
10.1007/BF00341273
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
440 patients were prospectively enrolled in a randomized, multicenter trial to compare 4 types of manual (84 interrupted end-to-end, 77 continuous end-to-end, 82 interrupted end-to-side, and 91 continuous end-to-side) (polyglycolic derived suture) and 1 type of stapled (106 side-to-side with GIA + TA devices) ileocolonic anastomosis after right hemicolectomy for carcinoma. The trial was designed according to Schwartz' pragmatic formulation. All 5 groups were well-matched, except for a lower rate of intraoperative sepsis in the stapled group (P < 0.02). The main end point was anastomotic leakage detected clinically or by routine sodium diatrizoate enema on the 8-10th postoperative day. Results showed that stapled ileocolonic anastomosis was associated with less anastomotic leakages (2.8 %) than all the other techniques combined (8.3 %). In spite of the fact that staples are approximately ten times more expensive, our results suggest performing side-to-side (GIA + TA) mechanical anastomosis after right resection for carcinoma.
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页码:29 / 33
页数:5
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