SELECTIVE-INHIBITION OF ACETAMINOPHEN OXIDATION AND TOXICITY BY CIMETIDINE AND OTHER HISTAMINE H2-RECEPTOR ANTAGONISTS INVIVO AND INVITRO IN THE RAT AND IN MAN

被引：67

作者：

MITCHELL, MC

SCHENKER, S

SPEEG, KV

机构：

[1] UNIV TEXAS,HLTH SCI CTR,DEPT MED,SAN ANTONIO,TX 78284

[2] JOHNS HOPKINS UNIV,SCH MED,DEPT MED,BALTIMORE,MD 21205

[3] AUDIE L MURPHY MEM VET HOSP,SAN ANTONIO,TX 78284

来源：

关键词：

D O I：

10.1172/JCI111223

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

引用

页码：383 / 391

页数：9

共 34 条

[1] ABERNETHY DR, 1983, J PHARMACOL EXP THER, V224, P508
[2] CORCORAN GB, 1980, MOL PHARMACOL, V18, P536
[3] CROME P, 1976, LANCET, V2, P829
[4] A KINETIC STUDY OF DRUG ELIMINATION - EXCRETION OF PARACETAMOL AND ITS METABOLITES IN MAN
CUMMINGS, AJ
KING, ML
MARTIN, BK
[J]. BRITISH JOURNAL OF PHARMACOLOGY AND CHEMOTHERAPY, 1967, 29 (02): : 150 - &
[5] CIMETIDINE IMPAIRS ELIMINATION OF CHLORDIAZEPOXIDE (LIBRIUM) IN MAN
DESMOND, PV
PATWARDHAN, RV
SCHENKER, S
SPEEG, KV
[J]. ANNALS OF INTERNAL MEDICINE, 1980, 93 (02) : 266 - 268
[6] EFFECT OF CIMETIDINE AND OTHER ANTI-HISTAMINICS ON THE ELIMINATION OF AMINOPYRINE, PHENACETIN AND CAFFEINE
DESMOND, PV
PATWARDHAN, R
PARKER, R
SCHENKER, S
SPEEG, KV
[J]. LIFE SCIENCES, 1980, 26 (15) : 1261 - 1268
[7] Dixon M., 1979, ENZYMES, P332
[8] INHIBITORY ACTION OF MERSALYL ON MICROSOMAL DRUG OXIDATION - RIGID ORGANIZATION OF ELECTRON TRANSPORT CHAIN
FRANKLIN, MR
ESTABROOK, RW
[J]. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1971, 143 (01) : 318 - +
[9] GOLDSTEIN M, 1979, RES COMMUN CHEM PATH, V23, P203
[10] ACETAMINOPHEN-INDUCED HEPATIC NECROSIS .6. METABOLIC DISPOSITION OF TOXIC AND NONTOXIC DOSES OF ACETAMINOPHEN
JOLLOW, DJ
THORGEIRSSON, SS
POTTER, WZ
HASHIMOTO, M
MITCHELL, JR
[J]. PHARMACOLOGY, 1974, 12 (4-5) : 251 - 271