A NEW CYCLOPYROPHOSPHATE AS A BACTERIAL ANTISTRESSOR

被引：23

作者：

OSTROVSKY, D

SHIPANOVA, I

SIBELDINA, L

SHASHKOV, A

KHARATIAN, E

MALYAROVA, I

TANTSYREV, G

机构：

[1] ACAD SCI USSR,INST CHEM RES,MOSCOW V-71,USSR

[2] ACAD SCI USSR,INST ORGAN CHEM,MOSCOW V-71,USSR

来源：

FEBS LETTERS | 1992年 / 298卷 / 2-3期

关键词：

OXIDATIVE STRESS; BACTERIUM; CYCLOPYROPHOSPHATE;

D O I：

10.1016/0014-5793(92)80045-I

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In a number of bacteria an unusual glycosyl pyrophosphate (P-31 NMR signal chemical shift at about -15 ppm) was detected when the cells were subjected to oxidative stress. This substance from Brevibacterium ammoniagenes has now been identified as 2-methyl-butan-1,2,3,4-tetraol 2,4-cyclopyrophosphate, which is accumulated in the cell under certain conditions in concentrations of about 50 mM. It is now suggested that this compound is the long sought after bacterial antistressor.

引用

页码：159 / 161

页数：3

共 8 条

[1] 2,3-CYCLOPYROPHOSPHOGLYCERATE IN METHANOGENS - EVIDENCE BY C-13 NMR-SPECTROSCOPY FOR A ROLE IN CARBOHYDRATE-METABOLISM [J].