PARKINSONS-DISEASE AND CYTOCHROME-P450 - A POSSIBLE LINK

被引:17
作者
SHAHI, GS
DAS, NP
MOOCHHALA, SM
机构
[1] NATL UNIV SINGAPORE,DEPT BIOCHEM,SINGAPORE 0511,SINGAPORE
[2] NATL UNIV SINGAPORE,DEPT PHARMACOL,SINGAPORE 0511,SINGAPORE
关键词
D O I
10.1016/0306-9877(90)90106-O
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
The possibility that idiopathic Parkinson's disease may be linked to a deficiency of an important detoxifying enzyme such as the cytochrome P450 enzyme bufuralol hydroxylase is examined. A hypothetical model of how this might operate to produce early onset Parkinson's disease is suggested. © 1990.
引用
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页码:277 / 282
页数:6
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