MOLECULAR CONNECTIVITY .1. RELATIONSHIP TO NONSPECIFIC LOCAL ANESTHESIA

被引：351

作者：

KIER, LB

HALL, LH

MURRAY, WJ

RANDIC, M

机构：

[1] MASSACHUSETTS COLL PHARM,BOSTON,MA 02115

[2] TUFTS UNIV,MEDFORD,MA 02155

来源：

JOURNAL OF PHARMACEUTICAL SCIENCES | 1975年 / 64卷 / 12期

关键词：

D O I：

10.1002/jps.2600641214

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：1971 / 1974

页数：4

共 11 条

[1] ACTION OF ANESTHETICS ON EXCITABLE MEMBRANES - A QUANTUM-CHEMICAL ANALYSIS [J].

AGIN, D ;

HERSH, L ;

HOLTZMAN, D .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1965, 53 (05) :952-&

[2] SOLUBILITY OF NONELECTROLYTES IN POLAR-SOLVENTS .2. SOLUBILITY OF ALIPHATIC-ALCOHOLS IN WATER [J].

AMIDON, GL ;

YALKOWSKY, SH ;

LEUNG, S .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1974, 63 (12) :1858-1866

[3]

CLAVERIE P, 1969, INT J QUANTUM CHEM, V3, P535

[4] THEORY OF HYDROPHOBIC BONDING .2. CORRELATION OF HYDROCARBON SOLUBILITY IN WATER WITH SOLVENT CAVITY SURFACE-AREA [J].

HERMANN, RB .

JOURNAL OF PHYSICAL CHEMISTRY, 1972, 76 (19) :2754-&

[5]

HOLTJE HD, 1974, J MED CHEM, V17, P814

[6] STRUCTURE-ACTIVITY STUDIES OF ENZYME SUBSTRATES USING MODEL INTERACTION CALCULATIONS [J].

HOLTJE, HD ;

KIER, LB .

JOURNAL OF THEORETICAL BIOLOGY, 1974, 48 (01) :197-205

[7]

HOLTJE HD, 1974, J PHARM SCI, V63, P1435

[8] MOLECULAR THEORY OF SWEET TASTE [J].

KIER, LB .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1972, 61 (09) :1394-+

[9]

LONDON F, 1936, DISCUSS FARADAY SOC, P8

[10]

RANDIC M, IN PRESS

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