CONSTITUENTS OF HALIMIUM-VISCOSUM .8. ENT-HALIMANE DITERPENES FROM HALIMIUM-VISCOSUM

被引：18

作者：

URONES, JG

MARCOS, IS

CUADRADO, JS

BASABE, P

BERTELLONI, AML

机构：

[1] Departamento de Quimica Organica. Facultad, Quimicas. Universidad de Salamanca, 37008 Salamanca

来源：

PHYTOCHEMISTRY | 1990年 / 29卷 / 04期

关键词：

Cistaceae; diterpenic acids; ent-halimanes; Halimium viscosum; reordered ent-labdanes; stereochemistry;

D O I：

10.1016/0031-9422(90)85435-I

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Together with two known acids, five new diterpenic acids with a reordered ent-labdane skeleton (ent-halimane) were isolated as the most polar components from the acidic fraction of Halimium viscosum as methyl esters. They were identified as methyl-(13S,14S)-epoxy-15-hydroxy-1(10)-ent-halimen-18-oate, methyl (13R,14R)-epoxy-15-hydroxy-1(10)-ent-halimen-18-oate, methyl-13R-hydroxy-14S,15-diacetoxy-1(10)-ent-halimen-18-oate, methyl-13S-hydroxy-14R,15-diacetoxy-1(10)-ent-halimen-18-oate and methyl-13S,15-dihydroxy-14-R-acetoxy-1(10)-ent-halimen-18-oate. The structure of these compounds was established by their spectroscopic data and then by hemisynthesis, allowing the assignment of the absolute configuration to be made at C-13 and C-14. © 1990.

引用

页码：1247 / 1251

页数：5