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AMITRIPTYLINE PRODUCES ANALGESIA IN THE FORMALIN PAIN TEST

被引：47
作者：
ACTON, J
MCKENNA, JE
MELZACK, R
机构：
[1] Department of Psychology, McGill University, Montreal, Que. H3A 1B1
来源：
EXPERIMENTAL NEUROLOGY | 1992年 / 117卷 / 01期
基金：
加拿大自然科学与工程研究理事会;
关键词：
D O I：
10.1016/0014-4886(92)90116-8
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
A dose of 20 mg/kg of amitriptyline reduced pain in the second phase of the formalin test, which is an animal model of long-lasting pain in humans. Since the analgesic effect was produced by a single dose, which is insufficient to produce an antidepressant effect, these results indicate that amitriptyline has analgesic properties that are independent of its antidepressant properties. © 1992.
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页码：94 / 96
页数：3
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