CHOLESTEROL AND OTHER CARDIOVASCULAR RISK-FACTORS IN A WORKING POPULATION IN ILE-DE-FRANCE (FRANCE) - 1ST RESULTS OF THE PCV-METRA STUDY

被引:10
作者
LAURIER, D [1 ]
CHAU, NP [1 ]
SEGOND, P [1 ]
机构
[1] UNIV PARIS 07,UNITE RECH BIOMATH & BIOSTAT,INSERM,U263,2 PL JUSSIEU,F-75251 PARIS 05,FRANCE
关键词
CHOLESTEROL; LIPOPROTEINS; SCREENING; CDV RISK FACTORS;
D O I
10.1007/BF00145386
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
In 1989, the French PCV-METRA Group (PCV-METRA = Prevention Cardio-Vasculaire en Medecine du Travail) started a large prospective survey of cardiovascular (CDV) morbidity and mortality and of CVD risk factors, especially cholesterol, in a working population in Ile-de-France, a region including Paris. This report presents the first results of this study, based on a sample of 5758 men and 2603 women, aged 18-65 years. The variables examined included the levels of total cholesterol (TC), High-density-liproprotein cholesterol (HDL-C), low-density-lipoprotein cholesterol (LDL-C), and the other major CVD risk factors (smoking, sedentary way of life, hypertension, hypercholesterolemia, use of oral contraceptives and familial history of CVD risks). TC and LDLC significantly increased with age. The changes with age were significantly different in men and women. The levels were similar in both sexes at less than 30 yrs, increased sharply for men after age 30 and were significantly higher in men than in women from 30 to 55 yrs. Beyond 55 yrs, no difference was obserbed between the two sexes. In contrast, HDL-C was higher in women at all age ranges. In the total sample, 35% of men and 21% of women were hypercholesterolemic (TC greater-than-or-equal-to 2.4 g/L). Our observations fully confirm and refine previous findings in the US and in other European countries. In addition, a substantial set of data on CVD risk factors for the working population in France, especially for female subjects for whom data are scanty, is now available.
引用
收藏
页码:693 / 701
页数:9
相关论文
共 29 条
[1]  
The cholesterol facts: a summary of the evidence relating dietary fats, serum cholesterol, and coronary heart disease, Circulation, 81, pp. 1721-1733, (1990)
[2]  
Berlin J.A., Colditz G., A meta-analysis of physical activity in the prevention of coronary heart disease, Am. J. Epidemiol., 132, pp. 612-628, (1990)
[3]  
Black D., James W.P.T., Besser G.M., Obesity. A report of the Royal College of Physicians, J. Royal College of Physicians of London, 17, pp. 5-65, (1983)
[4]  
Bloch C., Richard J.L., Les facteurs de risque des maladies par athérosclérose dans l'Etude Prospective Parisienne I. Comparison avec les études étrangères, Rev. Epidémiol. et Santé Publ., 33, pp. 108-120, (1985)
[5]  
Caggiula A.W., Christakis G., Farrand M., Multiple Risk Factors Intervention Trial (MRFIT), IV: intervention on blood lipids, Prev. Med., 10, pp. 443-475, (1984)
[6]  
Cambien F., Chretien J.M., Ducimetiere P., Guize L., Richard J.L., Is the relationship between blood pressure and Cardiovascular risk dependant on Body Mass Index?, Am. J. Epidemiol., 122, pp. 434-442, (1985)
[7]  
Castelli W.P., The triglyceride issue: a view from Framingham, Am. Heart J., 112, pp. 432-437, (1986)
[8]  
Douste-Blazy P., Ruidavest J.B., Arveiller D., Facteurs de risque cardio-vasculaire dans la population de deux regions couvertes par les registres MONICA-FRANCE: Strasbourg et Toulouse, Rev. Epidémiol. et Santé Publ., 36, pp. 342-349, (1988)
[9]  
Ducimetiere P., Richard J.I., Cambien F., Rakotovao R., Claude J.R., Coronary heart disease in middle-aged Frenchmen
[10]  
comparisons between Paris Prospective Study, Seven Countries Study, and Pooling Project, The Lancet, 1, pp. 1346-1350, (1980)