A CRITICAL-REVIEW OF PERMEABILIZED CELL SYSTEMS FOR STUDYING MAMMALIAN DNA-REPAIR

被引：55

作者：

KEENEY, S ^{[1
]}

LINN, S ^{[1
]}

机构：

[1] UNIV CALIF BERKELEY, DIV BIOCHEM & MOLEC BIOL, BERKELEY, CA 94720 USA

来源：

MUTATION RESEARCH | 1990年 / 236卷 / 2-3期

关键词：

ATP; in DNA repair; DNA polymerase enzymology; DNA repair; mammalian; Permeabilized cell systems;

D O I：

10.1016/0921-8777(90)90008-S

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Permeabilized cell systems have proven valuable for studies of the enzymology of mammalian DNA repair and this review will summarize and contrast the different systems used to this end. Results from permeable cell studies will be reviewed which pertain to 3 questions of DNA repair: the role(s) of ATP, DNA polymerase enzymology, and the isolation of repair factors by in vitro correction of repair-defective cells. © 1990.

引用

页码：239 / 252

页数：14

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