3-HYDROXY-3-METHYLGLUTARYL-COENZYME-A REDUCTASE INHIBITORS .2. STRUCTURAL MODIFICATION OF 7-(SUBSTITUTED ARYL)-3,5-DIHYDROXY-6-HEPTENOIC ACIDS AND THEIR LACTONE DERIVATIVES

被引:54
作者
HOFFMAN, WF [1 ]
ALBERTS, AW [1 ]
CRAGOE, EJ [1 ]
DEANA, AA [1 ]
EVANS, BE [1 ]
GILFILLAN, JL [1 ]
GOULD, NP [1 ]
HUFF, JW [1 ]
NOVELLO, FC [1 ]
PRUGH, JD [1 ]
RITTLE, KE [1 ]
SMITH, RL [1 ]
STOKKER, GE [1 ]
WILLARD, AK [1 ]
机构
[1] MERCK SHARP & DOHME RES LABS,RAHWAY,NJ 07065
关键词
D O I
10.1021/jm00152a001
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
引用
收藏
页码:159 / 169
页数:11
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