TISSUE LIPOPEROXIDATION AND GLUTATHIONE-PEROXIDASE ACTIVITY IN PUROMYCIN AMINONUCLEOSIDE INJECTED RATS

被引：7

作者：

PEDRAZACHAVERRI, J

AREVALO, AE

机构：

来源：

INTERNATIONAL JOURNAL OF BIOCHEMISTRY | 1994年 / 26卷 / 09期

关键词：

D O I：

10.1016/0020-711X(94)90136-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

1. Lipoperoxidation (LPx) and glutathione peroxidase (GPx) activity were measured in kidney, liver, heart, lung, brain and testis from control and puromycin aminonucleoside (PAN) injected rats on days 1-6, 8, 10, 16 and 22 after vehicle or PAN injection. 2. PAN-injected rats developed proteinuria on day 3. 3. In PAN-injected rats: (a) LPx increased in kidney, liver, lung, brain and testis before day 3 and in heart on day 3; (b) GPx activity increased in kidney, liver, heart, lung and testis and diminished in brain on day 3 or after.

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页码：1139 / 1145

页数：7

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