SIMULTANEOUS HPLC DETERMINATION OF SOME DRUGS COMMONLY USED IN COLD MEDICATIONS - DEXTROMETHORPHAN, DIPHENHYDRAMINE, PHENYLEPHRINE, PHENYLPROPANOLAMINE AND PSEUDOEPHEDRINE

被引：31

作者：

CARABALLO, I

FERNANDEZAREVALO, M

HOLGADO, MA

ALVAREZFUENTES, J

RABASCO, AM

机构：

[1] Departamento de Farmacia y Tecnología Farmacéutica, Facultad de Farmacia, Universidad de Sevilla. Prof. García, 41012, Sevilla, González s/n

来源：

DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY | 1995年 / 21卷 / 05期

关键词：

D O I：

10.3109/03639049509048126

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

In the present paper, a simple, direct, accurate and sensitive HPLC method applied over combinations of dextromethorphan, diphenhydramine, phenylephrine, phenylpropanolamine and pseudoephedrine is presented. The use of alumina particles bonded with polybutadiene as stationary phase allows the use of an alkaline mobile phase which provides an important improvement of the assay.

引用

页码：605 / 613

页数：9

共 6 条

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