A PHARMACOKINETIC PHARMACODYNAMIC RECEPTOR-BINDING MODEL TO PREDICT THE ONSET AND DURATION OF PHARMACOLOGICAL ACTIVITY OF THE BENZODIAZEPINES

被引：36

作者：

JACK, ML ^{[1
]}

COLBURN, WA ^{[1
]}

SPIRT, NM ^{[1
]}

BAUTZ, G ^{[1
]}

ZANKO, M ^{[1
]}

HORST, WD ^{[1
]}

OBRIEN, RA ^{[1
]}

机构：

[1] HOFFMANN LA ROCHE INC,DEPT PHARMACOL 2,NUTLEY,NJ 07110

来源：

关键词：

D O I：

10.1016/0278-5846(83)90036-2

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

引用

页码：629 / 635

页数：7

共 24 条

[1] LORAZEPAM - A REVIEW OF ITS CLINICAL PHARMACOLOGICAL PROPERTIES AND THERAPEUTIC USES
AMEER, B
GREENBLATT, DJ
[J]. DRUGS, 1981, 21 (03) : 161 - 200
[2] PLASMA-LEVEL OF DIAZEPAM AS A THERAPEUTIC PREDICTOR IN ANXIETY-STATES
BIANCHI, GN
FENNESSY, MR
PHILLIPS, J
EVERITT, BS
[J]. PSYCHOPHARMACOLOGIA, 1974, 35 (02): : 113 - 122
[3] SIMULTANEOUS PHARMACOKINETIC AND PHARMACODYNAMIC MODELING
COLBURN, WA
[J]. JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS, 1981, 9 (03): : 367 - 388
[4] DASBERG HH, 1974, CLIN PHARMACOL THER, V15, P473
[5] COMPARISON OF THE ACTIONS OF DIAZEPAM AND LORAZEPAM
DUNDEE, JW
MCGOWAN, WAW
LILBURN, JK
MCKAY, AC
HEGARTY, JE
[J]. BRITISH JOURNAL OF ANAESTHESIA, 1979, 51 (05) : 439 - 446
[6] FRIEDEL RO, 1981, CLIN PHARM PSYCHIATR
[7] GIBALDI M, 1975, PHARMACOKINETICS
[8] CLINICAL PHARMACOKINETICS OF LORAZEPAM .3. INTRAVENOUS-INJECTION - PRELIMINARY-RESULTS
GREENBLATT, DJ
COMER, WH
ELLIOTT, HW
SHADER, RI
KNOWLES, JA
RUELIUS, HW
[J]. JOURNAL OF CLINICAL PHARMACOLOGY, 1977, 17 (8-9) : 490 - 494
[9] PHARMACOKINETICS AND BIOAVAILABILITY OF INTRAVENOUS, INTRAMUSCULAR, AND ORAL LORAZEPAM IN HUMANS
GREENBLATT, DJ
SHADER, RI
FRANKE, K
MACLAUGHLIN, DS
HARMATZ, JS
ALLEN, MD
WERNER, A
WOO, E
[J]. JOURNAL OF PHARMACEUTICAL SCIENCES, 1979, 68 (01) : 57 - 63
[10] HILLESTA.L, 1974, CLIN PHARMACOL THER, V16, P485