AN ANTIMICROBIAL ALKALOID FROM FICUS-SEPTICA

被引：109

作者：

BAUMGARTNER, B ^{[1
]}

ERDELMEIER, CAJ ^{[1
]}

WRIGHT, AD ^{[1
]}

RALI, T ^{[1
]}

STICHER, O ^{[1
]}

机构：

[1] UNIV PAPUA NEW GUINEA,DEPT CHEM,PORT MORESBY,PAPUA N GUINEA

来源：

PHYTOCHEMISTRY | 1990年 / 29卷 / 10期

关键词：

antimicrobial activity; Ficus septica; indolizidine alkaloids; leaves; Moraceae;

D O I：

10.1016/0031-9422(90)80209-Y

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A methanolic extract ofFicus septica leaves displayed intense antibacterial and antifungal activities. Bioactivity-guided fractionation with TLC bioautography led to the isolation of two indolizidine alkaloids, the novel ficuseptine, 4,6-bis-(4-methoxyphenyl)- 1,2,3-trihydroindolizidinium chloride, and antofine. The structure of ficuseptine was determined from mass spectrometry and extensive one and two dimensional NMR spectroscopy. Complete1H and13C NMR assignments for antofine are reported. © 1990 Pergamon Press plc.

引用

页码：3327 / 3330

页数：4

共 10 条

[1] BALTISBERGER M, 1989, BER GEOBOT I ETH, V55, P252
[2] SYNTHESIS OF PHENANTHROINDOLIZIDINES .2. SYNTHESIS OF (+/-)-TYLOCREBRINE, (+/-)-TYLOPHORINE, (+/-)-ANTOFINE, AND (+/-)-2,3-DI ETHOXYPHENANTHROINDOLIZIDINE
CHAUNCY, B
GELLERT, E
[J]. AUSTRALIAN JOURNAL OF CHEMISTRY, 1970, 23 (12) : 2503 - &
[3] Cordell G.A., 1981, INTRO ALKALOIDS BIOG, P567, DOI 10.1002/jps.2600720334
[4] FERENCZY L, 1965, ACTA MICROBIOL HUNG, V12, P337
[5] ALKALOIDS OF FICUS-SEPTICA
HERBERT, RB
MOODY, CJ
[J]. PHYTOCHEMISTRY, 1972, 11 (03) : 1184 - &
[6] HOLDSWORTH D, 1981, Quarterly Journal of Crude Drug Research, V19, P155
[7] HOLDSWORTH D, 1986, International Journal of Crude Drug Research, V24, P217
[8] HOLDSWORTH D K, 1980, Quarterly Journal of Crude Drug Research, V18, P131
[9] ALKALOIDS OF FICUS SPECIES- OCCURRENCE OF INDOLIZIDINE ALKALOIDS IN FICUS SEPTICA
RUSSEL, JH
[J]. NATURWISSENSCHAFTEN, 1963, 50 (12) : 443 - &
[10] ALKALOIDS FROM CYNANCHUM VINCETOXICUM (L) PERS
WIEGREBE, W
FABER, L
BROCKMAN.H
BUDZIKIE.H
KRUGER, U
[J]. ANNALEN DER CHEMIE-JUSTUS LIEBIG, 1969, 721 (MAR): : 154 - &

← 1 →