AN IMPROVED METHOD FOR THE PREPARATION OF FORMYLDEUTEROPORPHYRINS - SYNTHESIS OF BIOLOGICALLY RELEVANT PORPHYRINS

被引：18

作者：

MONTFORTS, FP

SCHEURICH, G

MEIER, A

HAAKE, G

HOPER, F

机构：

[1] Institut für Organische Chemie, FB 2 Biologic/Chemie, 2800 Bremen 33

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 29期

关键词：

D O I：

10.1016/0040-4039(91)80810-S

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Pure 3 and 8 formyldeuteroporphyrin dimethylester isomers 3a,b have been prepared in high yield by formylation of readily accessible deuteroporphyrin dimethylester 1 with trimethyl orthoformate in trifluoroacetic acid and subsequent chromatographic separation of the mixture of isomers. The formylporphyrins can be transformed into synthetically and biologically useful derivatives.

引用

页码：3477 / 3480

页数：4

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