ROLE OF IRON, CAPSULE, AND TOXINS IN THE PATHOGENICITY OF VIBRIO-VULNIFICUS BIOTYPE-2 FOR MICE

被引：68

作者：

AMARO, C ^{[1
]}

BIOSCA, EG ^{[1
]}

FOUZ, B ^{[1
]}

TORANZO, AE ^{[1
]}

GARAY, E ^{[1
]}

机构：

[1] UNIV SANTIAGO DE COMPOSTELA,FAC BIOL,DEPT MICROBIOL,E-15706 SANTIAGO,SPAIN

来源：

INFECTION AND IMMUNITY | 1994年 / 62卷 / 02期

关键词：

D O I：

10.1128/IAI.62.2.759-763.1994

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The virulence mechanisms of Vibrio vulnificus biotype 2 have been studied and compared with those of biotype 1 in mice as the experimental animals. Biotype 2 isolates from European eels were as virulent for mice as biotype 1 strains (50% lethal dose, about 10(5) CFU per mouse); a septicemic infection developed in less than 24 h. These strains had several properties in common with biotype 1 organisms including capsule expression, uptake of various iron sources, and production of exoproteins, whose role in mouse virulence has been demonstrated. We also discuss the implication of biotype 2 strains in human infections.

引用

页码：759 / 763

页数：5

共 26 条

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