REPLICATION OF PARVOVIRUS-B19 IN HEMATOPOIETIC PROGENITOR CELLS GENERATED INVITRO FROM NORMAL HUMAN PERIPHERAL-BLOOD

被引：37

作者：

SCHWARZ, TF

SERKE, S

HOTTENTRAGER, B

VONBRUNN, A

BAURMANN, H

KIRSCH, A

STOLZ, W

HUHN, D

DEINHARDT, F

ROGGENDORF, M

机构：

[1] UNIV MUNICH,DERMATOL CLIN,W-8000 MUNICH 2,GERMANY

[2] FREE UNIV BERLIN,INTERNAL MED CLIN,DEPT HEMATOL & ONCOL,W-1000 BERLIN 33,GERMANY

[3] FREE UNIV BERLIN,KLINIKUM CHARLOTTENBURG,CLIN RUDOLF VIRCHOW,W-1000 BERLIN 19,GERMANY

来源：

JOURNAL OF VIROLOGY | 1992年 / 66卷 / 02期

关键词：

D O I：

10.1128/JVI.66.2.1273-1276.1992

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Erythroid progenitor cells generated in vitro from peripheral human blood in the presence of interleukin-3 and erythropoietin were infected with human parvovirus B19. B19 virus DNA replication was highest 48 to 72 h after infection, and maximum levels of B19 virus proteins were detected in culture supernatants at 72 to 96 h after infection. B19 virus propagated in vitro was infections. This cell culture system with peripheral blood cells facilitates studies in vitro of B19 virus replication.

引用

页码：1273 / 1276

页数：4

共 24 条

[1] AN OUTBREAK OF ERYTHEMA INFECTIOSUM ASSOCIATED WITH HUMAN PARVOVIRUS INFECTION [J].