AN ANTIBODY FRAGMENT AGAINST PAI-1 INHIBITS PAI-1 ACTIVITY AND STIMULATES FIBRINOLYSIS IN-VITRO AND IN-VIVO

被引：11

作者：

ABRAHAMSSON, T

BJORQUIST, P

DEINUM, J

EHNEBOM, J

HULANDER, M

LEGNEHED, A

MATSSON, C

NERME, V

WESTINERIKSSON, A

AKERBLOM, B

机构：

[1] Astra Hässle AB

来源：

FIBRINOLYSIS | 1994年 / 8卷

关键词：

PAI-1; T-PA; FIBRINOLYSIS; INHIBITION; ANTIBODY;

D O I：

10.1016/0268-9499(94)90245-3

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The inhibition of PAI-1 (plasminogen activator inhibitor type 1) was studied in different systems, both in vivo and in vitro. The results unambiguously show that inhibition of PAI-1 can stimulate fibrinolysis.

引用

页码：55 / 56

页数：2