MENINGITIS CAUSED BY CANDIDA SPECIES - AN EMERGING PROBLEM IN NEUROSURGICAL PATIENTS

被引：82

作者：

NGUYEN, MH

YU, VL

机构：

[1] UNIV PITTSBURGH,MED CTR,DIV INFECT DIS,PITTSBURGH,PA 15213

[2] DEPT VET AFFAIRS MED CTR,PITTSBURGH,PA

来源：

CLINICAL INFECTIOUS DISEASES | 1995年 / 21卷 / 02期

关键词：

D O I：

10.1093/clinids/21.2.323

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 [免疫学];

摘要：

Three cases of candida meningitis were encountered in a 3-year period in our hospital; all occurred in neurosurgical patients. We describe these three cases and review the 15 cases of neurosurgery-related candida meningitis previously reported in the English-language literature. Data regarding these 18 patients formed the basis for our review. Most patients with candida meningitis had recently received antibacterial agents, and it is notable that 50% of patients suffered from antecedent bacterial meningitis. The CSF analysis revealed neutrophilic pleocytosis that was indistinguishable from that of bacterial meningitis. The overall mortality was 11%. Administration of amphotericin B combined with flucytosine appeared to be the best therapeutic approach for candida meningitis.

引用

页码：323 / 327

页数：5

共 26 条

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