ENT-12-OXOLABDA-8,13(16)-DIEN-15-OIC ACID AND ENT-8-BETA,12-ALPHA-EPIDIOXY-12-BETA-HYDROXYLABDA-9(11),13-DIEN-15-OIC ACID GAMMA-LACTONE - 2 NEW DITERPENES FROM THE AERIAL PARTS OF PREMNA-OLIGOTRICHA

被引：22

作者：

HABTEMARIAM, S

GRAY, AI

LAVAUD, C

MASSIOT, G

SKELTON, BW

WATERMAN, PG

WHITE, AH

机构：

[1] UNIV REIMS,FAC PHARM,CNRS,URA 492,PHARMACOGNOSIE LAB,F-51096 REIMS,FRANCE

[2] UNIV WESTERN AUSTRALIA,DEPT PHYS & INORGAN CHEM,NEDLANDS,WA 6009,AUSTRALIA

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1991年 / 04期

关键词：

D O I：

10.1039/p19910000893

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Two novel ent-labdane diterpenes have been isolated from the aerial parts of Premna oligotricha (Verbenaceae). Primarily through NMR studies one was identified as ent-12-oxolabda-8,13(16)-dien-15-oic acid. Similar analysis of the second diterpene was unable to distinguish between two possible structures, ent-8-beta,12-alpha-epidioxy-12-beta-hydroxylabda-9(11),13-dien-15-oic acid gamma-lactone and ent-8-beta,12-alpha-epoxy-12-beta-hydroperoxylabda-9(11),13-dien-15-oic acid delta-lactone. The structure of the second diterpene was established as the gamma-lactone by an X-ray diffraction study

引用

页码：893 / 896

页数：4

共 7 条

[1] H-1 AND C-13 ASSIGNMENTS FROM SENSITIVITY-ENHANCED DETECTION OF HETERONUCLEAR MULTIPLE-BOND CONNECTIVITY BY 2D MULTIPLE QUANTUM NMR [J].