CHEMOSELECTIVE CARBONYL REDUCTION MEDIATED BY LOW-VALENT TITANIUM

被引：5

作者：

ADAMS, CM

SCHEMENAUR, JE

机构：

[1] Department of Chemistry, Oklahoma State University, Stillwater, Oklahoma

来源：

SYNTHETIC COMMUNICATIONS | 1990年 / 20卷 / 15期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1080/00397919008053181

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Utilizing the rate difference in alkoxy alkyl radical formation from aldehydes versus ketones with low-valent titanium, aldehydes are preferentially reduced with tributyltin hydride. The difference in reactivity allows aldehydes to be reduced in the presence of ketones without laborious protection-deprotection steps. © 1990, Taylor & Francis Group, LLC. All rights reserved.

引用

页码：2359 / 2364

页数：6

共 16 条

[1] REDUCTION OF KETONES BY TRIBUTYLTIN HYDRIDE - THE EFFECT OF HIGH-PRESSURE ON STERIC HINDRANCE AND REARRANGEMENT PROCESSES [J].