THE THIAZOLIUM CATALYZED BENZOIN CONDENSATION WITH MILD BASE DOES NOT INVOLVE A DIMER INTERMEDIATE

被引：80

作者：

BRESLOW, R

KIM, R

机构：

[1] Department of Chemistry, Columbia University New York

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 05期

关键词：

D O I：

10.1016/S0040-4039(00)75794-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Kinetic studies show that the benzoin condensation catalyzed by 3,4,5-trimethylthiazolium iodide and triethylamine in DMSO has a transition state with two benzaldehyde and one thiazolium;components, while the conversion of nitrobenzaldehyde to the thiazolium adduct is kinetically first order in thiazolium salt and aldehyde. These findings exclude proposals that thiazolium dimers are the true catalytic species.

引用

页码：699 / 702

页数：4

共 15 条

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