ELEVATED PLASMA TISSUE FACTOR ANTIGEN LEVEL IN PATIENTS WITH DISSEMINATED INTRAVASCULAR COAGULATION

被引:64
作者
WADA, H
NAKASE, T
NAKAYA, R
MINAMIKAWA, K
WAKITA, Y
KANEKO, T
OHIWA, M
DEGUCHI, K
SHIRAKAWA, S
机构
[1] MIE UNIV,SCH MED,COLL MED SCI,TSU,MIE,JAPAN
[2] NAGAI HOSP,DEPT INTERNAL MED,NAGAI,JAPAN
关键词
TF; DIC;
D O I
10.1002/ajh.2830450307
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The plasma tissue factor (TF) antigen level was measured in patients with disseminated intravascular coagulation (DIC). The plasma TF antigen was detected in normal volunteers, and it was significantly higher in DIC patients than in non-DIC patients. However, in some patients with DIC, the plasma TF antigen level was within the normal range. The plasma TF antigen level in patients with DIC significantly decreased after therapy, but it was not correlated with organ failure or outcome. The plasma TF antigen level in patients with DIC was not correlated with other hemostatic markers. The plasma TF antigen level tended to be higher in DIC patients with nonlymphoid leukemia than in those with lymphoid tumor. TF might be implicated in the occurrence and progression of DIC. (C) 1994 Wiley-Liss, Inc.
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页码:232 / 236
页数:5
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