ACID HYDROLASES IN SKIN AND PLASMA IN GARGOYLISM DEFICIENCY OF BETA-GALACTOSIDASE IN SKIN

被引：127

作者：

OCKERMAN, PA

机构：

[1] Department of Clinical Chemistry, University of Lund

来源：

CLINICA CHIMICA ACTA | 1968年 / 20卷 / 01期

关键词：

D O I：

10.1016/0009-8981(68)90375-6

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

The activity of acid hydrolases was studied in skin and plasma in patients with gargoylism. The activity of β-galactosidase was found to be lower in skin in patients with gargoylism than in the controls. In plasma a higher activity than in the controls was found. Of the acid hydrolytic enzyme activities measured, those of β-glucuronidase and β-acetylglucosaminidase were significantly increased both in plasma and skin in patients with gargoylism. The validity of these findings and some possible explanations are discussed. © 1968.

引用

页码：1 / &

共 12 条

[1]

ARONSON SM, 1967, INBORN DISORDERS ED, P169

[2]

FISHMAN WH, 1953, J BIOL CHEM, V200, P89

[3]

GATT S, 1965, ISRAEL J MED SCI, V1, P624

[4]

HARJA A, 1966, J LIPID RES, V7, P379

[5]

HERS HG, 1965, GASTROENTEROLOGY, V48, P625

[6]

HERS HG, 1967, 4 M FED EUR BIOCH SO

[7]

LOWRY OH, 1951, J BIOL CHEM, V193, P265

[8] DIAGNOSIS OF HURLERS SYNDROME IN HOSPITAL LABORATORY AND DETERMINATION OF ITS GENETIC TYPE [J].

MANLEY, G ;

HAWKSWORTH, J .

ARCHIVES OF DISEASE IN CHILDHOOD, 1966, 41 (215) :91-+

[9]

MCKUSICK VA, 1966, HERITABLE DISORDERS

[10]

OCKERMAN PA, 1967, ACTA PAEDIATR SCAND, V177, P35

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