SURFACE-GRAFTED HEPARINIZABLE MATERIALS

被引：31

作者：

BARBUCCI, R

CASINI, G

FERRUTI, P

TEMPESTI, F

机构：

[1] CRISMA, Univ of Siena, Siena, Italy, CRISMA, Univ of Siena, Siena, Italy

来源：

POLYMER | 1985年 / 26卷

关键词：

CHEMICAL REACTIONS - Grafting;

D O I：

10.1016/0032-3861(85)90310-6

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Poly(amido-amine) chains have been grafted on the surface of different materials including glass, silastic, PVC, Dacron, and polyurethane. The poly(amido-amine) is able to complex with heparin by electrostatic interaction. The heparin-adsorbing capacity of the materials so obtained has been tested by biological tests. Heparin is only released at pH greater than 10, confirming the strong interaction between poly(amido-amine) and heparin. Preliminary theoretical studies have been made to construct a tentative model of the arrangement in the space of poly(amido-amine).

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页码：1349 / 1352

页数：4

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