RECA PROTEIN IN THE SOS RESPONSE - MILESTONES AND MYSTERIES

被引:61
作者
WITKIN, EM
机构
[1] Waksman Institute of Microbiology, Rutgers, the State University of New Jersey, Piscataway, NJ 08854
关键词
LEXA PROTEIN; ULTRAVIOLET LIGHT; PROPHAGE INDUCTION; DNA REPAIR; SOS MUTAGENESIS;
D O I
10.1016/0300-9084(91)90196-8
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The role of RecA protein in the SOS response of Escherichia coli is traced from the isolation of the first recA mutant to our current understanding of the scope and regulation of this DNA damage-inducible system. In addition, possible RecA protein activities that may be essential in the expression of several SOS phenotypes (stable DNA replication, DNA replication recovery, SOS mutagenesis and RecA association with the cell membrane) are discussed.
引用
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页码:133 / 141
页数:9
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