ABSENCE OF STRUCTURAL REARRANGEMENTS OF CHROMOSOME-11 IN HUMAN PRIMARY MALIGNANT-MELANOMA

被引：7

作者：

NEDOSZYTKO, B ^{[1
]}

MROZEK, K ^{[1
]}

LIMON, J ^{[1
]}

机构：

[1] MED ACAD GDANSK,DEPT BIOL & GENET,1 DEBINKI ST,PL-80211 GDANSK,POLAND

来源：

CANCER GENETICS AND CYTOGENETICS | 1992年 / 58卷 / 02期

关键词：

D O I：

10.1016/0165-4608(92)90112-L

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Cytogenetic analysis of 10 primary and 18 metastatic malignant melanomas revealed that structural abnormalities of chromosome 11 were present in 50% of metastatic lesions and were not found in primary tumors. Our findings suggest that chromosome 11 aberrations represent secondary changes in malignant melanoma tumorigenesis.

引用

页码：196 / 197

页数：2

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