DISRUPTION OF HUMAN CIRCADIAN AND COGNITIVE REGULATION FOLLOWING A DISCRETE HYPOTHALAMIC-LESION - A CASE-STUDY

被引:133
作者
COHEN, RA
ALBERS, HE
机构
[1] UNIV MASSACHUSETTS,SCH MED,DEPT PSYCHIAT,WORCESTER,MA 01605
[2] GEORGIA STATE UNIV,NEUROENDOCRINOL & BEHAV LAB,ATLANTA,GA 30303
[3] GEORGIA STATE UNIV,DEPT BIOL,ATLANTA,GA 30303
[4] GEORGIA STATE UNIV,DEPT PSYCHOL,ATLANTA,GA 30303
关键词
D O I
10.1212/WNL.41.5.726
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
We report a patient with rostral hypothalamic damage that significantly disrupted temporal patterning of the sleep-wake cycle, body temperature, and cognitive and behavioral functioning. The findings suggest that the suprachiasmatic region of the hypothalamus is important for the circadian control of human behavior, and that circadian organization may be essential for normal cognitive functioning.
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页码:726 / 729
页数:4
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