HEPATITIS-E VIRUS - THE CAUSE OF A WATERBORNE HEPATITIS OUTBREAK

被引：58

作者：

SKIDMORE, SJ ^{[1
]}

YARBOUGH, PO ^{[1
]}

GABOR, KA ^{[1
]}

REYES, GR ^{[1
]}

机构：

[1] GENELABS INC,DEPT MOLEC VIROL,REDWOOD CITY,CA

来源：

JOURNAL OF MEDICAL VIROLOGY | 1992年 / 37卷 / 01期

关键词：

ASSAYS FOR ANTI-HEV; HEV ELISA; KASHMIR; VIRAL HEPATITIS; ANICTERIC HEPATITIS;

D O I：

10.1002/jmv.1890370110

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Newly developed assays for antibody to hepatitis E virus (HEV) were used to study 114 serum samples collected during an outbreak of enterically transmitted hepatitis that occurred in Kashmir in 1978/9. The sera included samples from patients with viral hepatitis, anicteric hepatitis, contacts of cases, and unaffected persons. A total of 71% of patients with viral hepatitis were found positive for anti-HEV specific IgG, and 75% of these were also positive for IgM. These data confirm the hepatitis E virus as the causative agent in this outbreak.

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页码：58 / 60

页数：3

相关论文

共 15 条

[1] ETIOLOGICAL AGENT OF ENTERICALLY TRANSMITTED NON-A-HEPATITIS, NON-B-HEPATITIS [J].

BRADLEY, D ;

ANDJAPARIDZE, A ;

COOK, EH ;

MCCAUSTLAND, K ;

BALAYAN, M ;

STETLER, H ;

VELAZQUEZ, O ;

ROBERTSON, B ;

HUMPHREY, C ;

KANE, M ;

WEISFUSE, I .

JOURNAL OF GENERAL VIROLOGY, 1988, 69 :731-738

[2] ENTERICALLY-TRANSMITTED NON-A, NON-B HEPATITIS [J].

BRADLEY, DW .

BRITISH MEDICAL BULLETIN, 1990, 46 (02) :442-461

[3] INCIDENCE AND SEVERITY OF VIRAL-HEPATITIS IN PREGNANCY [J].

KHUROO, MS ;

TELI, MR ;

SKIDMORE, S ;

SOFI, MA ;

KHUROO, MI .

AMERICAN JOURNAL OF MEDICINE, 1981, 70 (02) :252-255

[4] STUDY OF AN EPIDEMIC OF NON-A, NON-B HEPATITIS - POSSIBILITY OF ANOTHER HUMAN HEPATITIS-VIRUS DISTINCT FROM POST-TRANSFUSION NON-A, NON-B TYPE [J].

KHUROO, MS .

AMERICAN JOURNAL OF MEDICINE, 1980, 68 (06) :818-824

[5]

PURCELL RH, 1988, VIRAL HEPATITIS LIVE, P131

[6]

RAMALINGASWAMI V, 1988, LANCET, V1, P571

[7] ISOLATION OF A CDNA FROM THE VIRUS RESPONSIBLE FOR ENTERICALLY TRANSMITTED NON-A, NON-B HEPATITIS [J].

REYES, GR ;

PURDY, MA ;

KIM, JP ;

LUK, KC ;

YOUNG, LM ;

FRY, KE ;

BRADLEY, DW .

SCIENCE, 1990, 247 (4948) :1335-1339

[8] SINGLE-STEP PURIFICATION OF POLYPEPTIDES EXPRESSED IN ESCHERICHIA-COLI AS FUSIONS WITH GLUTATHIONE S-TRANSFERASE [J].

SMITH, DB ;

JOHNSON, KS .

GENE, 1988, 67 (01) :31-40

[9] HEPATITIS-E VIRUS (HEV) - MOLECULAR-CLONING AND SEQUENCING OF THE FULL-LENGTH VIRAL GENOME [J].

TAM, AW ;

SMITH, MM ;

GUERRA, ME ;

HUANG, CC ;

BRADLEY, DW ;

FRY, KE ;

REYES, GR .

VIROLOGY, 1991, 185 (01) :120-131

[10] ELECTROPHORETIC TRANSFER OF PROTEINS FROM POLYACRYLAMIDE GELS TO NITROCELLULOSE SHEETS - PROCEDURE AND SOME APPLICATIONS [J].

TOWBIN, H ;

STAEHELIN, T ;

GORDON, J .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1979, 76 (09) :4350-4354