CONTROLLED EVALUATION OF A BANDAGE CONTACT-LENS AND A TOPICAL NONSTEROIDAL ANTIINFLAMMATORY DRUG IN TREATING TRAUMATIC CORNEAL ABRASIONS

被引:49
作者
DONNENFELD, ED
SELKIN, BA
PERRY, HD
MOADEL, K
SELKIN, GT
COHEN, AJ
SPERBER, LTB
机构
[1] MANHATTAN EYE EAR & THROAT HOSP,NEW YORK,NY 10021
[2] LENNOX HILL HOSP,NEW YORK,NY
关键词
D O I
10.1016/S0161-6420(95)30926-8
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Background: Treating traumatic corneal abrasions is a common problem for the ophthalmologist. Traditional management has been the use of a pressure patch. Three different therapeutic modalities were evaluated for their efficacy in treating traumatic corneal abrasions. Methods: Forty-seven consecutive patients with traumatic corneal abrasions were randomized prospectively in a single-masked, controlled clinical trial which compared the efficacy of (1) pressure patching, (2) a bandage contact lens, and (3) a bandage contact lens with a topical nonsteroidal anti-inflammatory drug (0.5% ketorolac tromethamine). Results: There was no significant difference in the healing time of the three groups. However, psychometric analysis showed a significant decrease in pain in the group that received a bandage-contact lens with a topical nonsteroidal anti-inflammatory drug. There was a significant difference in the ability to return to normal activities in both contact lens groups compared with the pressure-patch group. There was no significant difference among the three groups with respect to photophobia, redness, ocular irritation, headache, or tearing. Conclusion: Use of a bandage contact lens significantly shortens the time required for a patient to return to normal activities. Moreover, addition of a nonsteroidal antiinflammatory drug to a treatment regimen significantly decreases the pain associated with traumatic corneal abrasions. Use of a bandage contact lens with a topical nonsteroidal anti-inflammatory may prove to be an effective adjunct in treating traumatic corneal abrasions.
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收藏
页码:979 / 984
页数:6
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