THE CHIP28 WATER CHANNEL VISUALIZED IN ICE BY ELECTRON CRYSTALLOGRAPHY

被引：69

作者：

MITRA, AK

VANHOEK, AN

WIENER, MC

VERKMAN, AS

YEAGER, M

机构：

[1] UNIV CALIF SAN FRANCISCO, CARDIOVASC RES INST, DEPT MED, SAN FRANCISCO, CA 94143 USA

[2] UNIV CALIF SAN FRANCISCO, CARDIOVASC RES INST, DEPT PHYSIOL, SAN FRANCISCO, CA 94143 USA

[3] UNIV CALIF SAN FRANCISCO, DEPT BIOPHYS & BIOCHEM, SAN FRANCISCO, CA 94143 USA

[4] SCRIPPS CLIN & RES FDN, DIV CARDIOVASC DIS, LA JOLLA, CA 92037 USA

来源：

NATURE STRUCTURAL BIOLOGY | 1995年 / 2卷 / 09期

关键词：

D O I：

10.1038/nsb0995-726

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Electron crystallography of frozen-hydrated two-dimensional crystals of deglycosylated human erythrocyte CHIP28 reveals an aqueous vestibule in each monomer leading to the water-selective channel that is enclosed by multiple transmembrane alpha-helices.

引用

页码：726 / 729

页数：4

共 34 条

[1] AGRE P, 1993, AM J PHYSIOL, V265, pF463
[2] IMAGES OF PURPLE MEMBRANE AT 2.8 A RESOLUTION OBTAINED BY CRYO-ELECTRON MICROSCOPY
BALDWIN, JM
HENDERSON, R
BECKMAN, E
ZEMLIN, F
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1988, 202 (03) : 585 - 591
[3] A LEAST-SQUARES REFINEMENT METHOD FOR ISOMORPHOUS REPLACEMENT
DICKERSO.RE
WEINZIER.JE
PALMER, RA
[J]. ACTA CRYSTALLOGRAPHICA SECTION B-STRUCTURAL CRYSTALLOGRAPHY AND CRYSTAL CHEMISTRY, 1968, B 24 : 997 - &
[4] FISCHBARG J, 1995, J MEMBRANE BIOL, V143, P177
[5] THE MAJOR INTRINSIC PROTEIN (MIP) OF THE BOVINE LENS FIBER MEMBRANE - CHARACTERIZATION AND STRUCTURE BASED ON CDNA CLONING
GORIN, MB
YANCEY, SB
CLINE, J
REVEL, JP
HORWITZ, J
[J]. CELL, 1984, 39 (01) : 49 - 59
[6] PROJECTION STRUCTURE OF HALORHODOPSIN FROM HALOBACTERIUM-HALOBIUM AT 6-ANGSTROM RESOLUTION OBTAINED BY ELECTRON CRYOMICROSCOPY
HAVELKA, WA
HENDERSON, R
HEYMANN, JAW
OESTERHELT, D
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1993, 234 (03) : 837 - 846
[7] MODEL FOR THE STRUCTURE OF BACTERIORHODOPSIN BASED ON HIGH-RESOLUTION ELECTRON CRYOMICROSCOPY
HENDERSON, R
BALDWIN, JM
CESKA, TA
ZEMLIN, F
BECKMANN, E
DOWNING, KH
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1990, 213 (04) : 899 - 929
[8] STRUCTURAL ARCHITECTURE OF AN OUTER-MEMBRANE CHANNEL AS DETERMINED BY ELECTRON CRYSTALLOGRAPHY
JAP, BK
WALIAN, PJ
GEHRING, K
[J]. NATURE, 1991, 350 (6314) : 167 - 170
[9] PEPTIDE-CHAIN SECONDARY STRUCTURE OF BACTERIORHODOPSIN
JAP, BK
MAESTRE, MF
HAYWARD, SB
GLAESER, RM
[J]. BIOPHYSICAL JOURNAL, 1983, 43 (01) : 81 - 89
[10] MOLECULAR DESIGN OF PHOE PORIN AND ITS FUNCTIONAL CONSEQUENCES
JAP, BK
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1989, 205 (02) : 407 - 419

← 1 2 3 4 →