CALCIUM-METABOLISM IN MALARIA-INFECTED ERYTHROCYTES

被引：12

作者：

KRISHNA, S ^{[1
]}

SQUIREPOLLARD, L ^{[1
]}

机构：

[1] UNIV LIVERPOOL, LIVERPOOL SCH TROP MED, DEPT PARASITOL, LIVERPOOL L3 5QA, ENGLAND

来源：

PARASITOLOGY TODAY | 1990年 / 6卷 / 06期

基金：

英国惠康基金;

关键词：

D O I：

10.1016/0169-4758(90)90356-9

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Changes in the concentration of free calcium regulate many intracellular metabolic pathways and other important aspects of cellular function. The erythrocyte maintains intracellular calcium concentrations within a narrow range, but infection by malarial parasites disrupts these homeostatic mechanisms. The observation that infected erythrocytes have supranormal concentrations of calcium raises questions about the storage and functions of calcium ions within parasites. These are addressed in the following review by Sanjeev Krishna and Laura Squire-Pollard. © 1990.

引用

页码：196 / 198

页数：3

共 21 条

[1] REVERSAL OF CHLOROQUINE RESISTANCE IN MALARIA PARASITE PLASMODIUM-FALCIPARUM BY DESIPRAMINE [J].