A NEW ROUTE TO HOMOCHIRAL PIPERIDINES

被引：48

作者：

JONES, RCF

TURNER, I

HOWARD, KJ

机构：

[1] Chemistry Department, Nottingham University, Nottingham

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 39期

关键词：

D O I：

10.1016/S0040-4039(00)73744-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of an enantiomeric pair of enaminoesters from phenylglycine is described. Conjugate addition to alpha,beta-enones, reductive cyclization-fragmentation to octahydroimidazopyridines and further reduction to remove the auxiliary atoms, completes a new route to homochiral piperidines in which the enaminoesters function as homochiral 'ethanal enamines'.

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页码：6329 / 6332

页数：4

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