THE COMPLETE AMINO-ACID-SEQUENCE OF THE FOLLITROPIN BETA-SUBUNIT OF THE BULLFROG, RANA-CATESBEIANA

被引：29

作者：

HAYASHI, T ^{[1
]}

HANAOKA, Y ^{[1
]}

HAYASHI, H ^{[1
]}

机构：

[1] GUNMA UNIV,INST ENDOCRINOL,DEPT PROT CHEM,MAEBASHI,GUNMA 371,JAPAN

来源：

GENERAL AND COMPARATIVE ENDOCRINOLOGY | 1992年 / 88卷 / 01期

关键词：

D O I：

10.1016/0016-6480(92)90203-V

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The amino acid sequence of the bullfrog, Rana catesbeiana, follitropin β-subunit has been determined by sequencing the intact protein (residues 1-39) and peptides originated by lysyl endopeptidase and pepsin. Twelve cysteine residues and two sugar chain binding sites at Asn-5 and Asn-22 are positional identities with bullfrog and mammalian β-subunits. The bullfrog FSH β-subunit is composed of 107 amino acid residues with a molecular mass of 11,782 Da, including the six cystine bridges and excepting the sugar chain. The bullfrog FSH β-subunit has approximately 60% sequence identity with that of mammals and 40% with the fish gonadotropin β-subunit. Conserved sequences among mammals (residue numbers 33-55 and 66-71) extensively differed from those of the bullfrog. © 1992.

引用

页码：144 / 150

页数：7

共 21 条

[1] PURIFICATION, CHARACTERIZATION, AND MOLECULAR-CLONING OF GONADOTROPIN SUBUNITS OF SILVER CARP (HYPOPHTHALMICHTHYS-MOLITRIX) [J].

CHANG, YS ;

HUANG, CJ ;

HUANG, FL ;

LIU, CS ;

LO, TB .

GENERAL AND COMPARATIVE ENDOCRINOLOGY, 1990, 78 (01) :23-33

[2]

CHANG YS, 1988, INT J PEPT PROT RES, V32, P556

[3] PORCINE FOLLITROPIN - AMINO-ACID-SEQUENCE OF BETA-SUBUNIT [J].

CLOSSET, J ;

MAGHUINROGISTER, G ;

HENNEN, G ;

STROSBERG, AD .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1978, 86 (01) :115-120

[4] A SYNTHETIC PEPTIDE CORRESPONDING TO HUMAN-FSH-BETA-SUBUNIT 33-53 BINDS TO FSH RECEPTOR, STIMULATES BASAL ESTRADIOL BIOSYNTHESIS, AND IS A PARTIAL ANTAGONIST OF FSH [J].

COLOMA, TAS ;

DATTATREYAMURTY, B ;

REICHERT, LE .

BIOCHEMISTRY, 1990, 29 (05) :1194-1200

[5]

CRESTFIELD AM, 1963, J BIOL CHEM, V238, P622

[6] CLONING AND DNA-SEQUENCE ANALYSIS OF THE CDNA FOR THE PRECURSOR OF THE BETA-CHAIN OF BOVINE FOLLICLE-STIMULATING-HORMONE [J].

ESCH, FS ;

MASON, AJ ;

COOKSEY, K ;

MERCADO, M ;

SHIMASAKI, S .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1986, 83 (17) :6618-6621

[7]

FRIEDMAN M, 1970, J BIOL CHEM, V245, P3868

[8]

FUJIKI Y, 1978, J BIOL CHEM, V253, P5363

[9]

HANAOKA Y, 1984, Gunma Symposia on Endocrinology, V21, P63

[10] AMPHIBIAN LUTROPIN FROM THE BULLFROG RANA-CATESBEIANA COMPLETE AMINO-ACID-SEQUENCE OF THE BETA SUBUNIT [J].

HAYASHI, H ;

HAYASHI, T ;

HANAOKA, Y .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1992, 205 (01) :105-110

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