TIANEPTINE, A NEW TRICYCLIC ANTIDEPRESSANT METABOLIZED BY BETA-OXIDATION OF ITS HEPTANOIC SIDE-CHAIN, INHIBITS THE MITOCHONDRIAL OXIDATION OF MEDIUM AND SHORT CHAIN FATTY-ACIDS IN MICE

被引：53

作者：

FROMENTY, B ^{[1
]}

FRENEAUX, E ^{[1
]}

LABBE, G ^{[1
]}

DESCHAMPS, D ^{[1
]}

LARREY, D ^{[1
]}

LETTERON, P ^{[1
]}

PESSAYRE, D ^{[1
]}

机构：

[1] HOP BEAUJON,INSERM,U24,UNITE RECH PHYSIOPATHOL HEPAT,F-92118 CLICHY,FRANCE

来源：

BIOCHEMICAL PHARMACOLOGY | 1989年 / 38卷 / 21期

关键词：

D O I：

10.1016/0006-2952(89)90580-7

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：3743 / 3751

页数：9

共 26 条

[1]

BOUYER I, 1988, PSYCHOPHARMACOLOGY S, V96, P275

[2] FACTORS CONTROLLING RATE OF FATTY-ACID BETA-OXIDATION IN RAT-LIVER MITOCHONDRIA [J].

BREMER, J ;

WOJTCZAK, AB .

BIOCHIMICA ET BIOPHYSICA ACTA, 1972, 280 (04) :515-530

[3] CARNITINE - METABOLISM AND FUNCTIONS [J].

BREMER, J .

PHYSIOLOGICAL REVIEWS, 1983, 63 (04) :1420-1480

[4] PIRPROFEN-INDUCED FULMINANT-HEPATITIS [J].

DANAN, G ;

TRUNET, P ;

BERNUAU, J ;

DEGOTT, C ;

BABANY, G ;

PESSAYRE, D ;

RUEFF, B ;

BENHAMOU, JP .

GASTROENTEROLOGY, 1985, 89 (01) :210-213

[5]

DELLALEAU B, 1988, CLIN NEUROPHARMAC S2, V11, P583

[6] INHIBITION OF THE MITOCHONDRIAL OXIDATION OF FATTY-ACIDS BY TETRACYCLINE IN MICE AND IN MAN - POSSIBLE ROLE IN MICROVESICULAR STEATOSIS INDUCED BY THIS ANTIBIOTIC [J].

FRENEAUX, E ;

LABBE, G ;

LETTERON, P ;

DINH, TL ;

DEGOTT, C ;

GENEVE, J ;

LARREY, D ;

PESSAYRE, D .

HEPATOLOGY, 1988, 8 (05) :1056-1062

[7]

GENEVE J, 1987, J PHARMACOL EXP THER, V242, P1133

[8] THE HEPATOTOXICITY OF VALPROIC ACID AND ITS METABOLITES IN RATS .1. TOXICOLOGIC, BIOCHEMICAL AND HISTOPATHOLOGIC STUDIES [J].

KESTERSON, JW ;

GRANNEMAN, GR ;

MACHINIST, JM .

HEPATOLOGY, 1984, 4 (06) :1143-1152

[9]

LEDINH T, 1988, J PHARMACOL EXP THER, V247, P745

[10]

LOWRY OH, 1951, J BIOL CHEM, V193, P265

← 1 2 3 →