STUDIES ON BIOACTIVE COMPOUNDS .13. SYNTHESIS AND LACK OF GROWTH-INHIBITORY PROPERTIES OF CYCLOHEXANE-1,2,4-TRIOL 1,2-DIESTERS, WHICH RESEMBLE RING-C OF THE PHORBOL ESTER MOLECULE

被引：10

作者：

LAUGHTON, CA ^{[1
]}

DALE, IL ^{[1
]}

GESCHER, A ^{[1
]}

机构：

[1] ASTON UNIV,INST PHARMACEUT SCI,CANC RES CAMPAIGN,EXPTL CHEMOTHERAPY GRP,BIRMINGHAM B4 7ET,ENGLAND

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1989年 / 32卷 / 02期

关键词：

D O I：

10.1021/jm00122a023

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：428 / 433

页数：6

共 28 条

[1] X-RAY STRUCTURE ANALYSIS OF NEOPHORBOL, C31H3509BR, AND PHORBOL, C20H2806 [J].

BRANDL, F ;

ROHRL, M ;

ZECHMEIS.K ;

HOPPE, W .

ACTA CRYSTALLOGRAPHICA SECTION B-STRUCTURAL CRYSTALLOGRAPHY AND CRYSTAL CHEMISTRY, 1971, B 27 (SEP15) :1718-&

[2] LITHIUM TRI-SEC-BUTYLBOROHYDRIDE - NEW REAGENT FOR REDUCTION OF CYCLIC AND BICYCLIC KETONES WITH SUPER STEREOSELECTIVITY - REMARKABLY SIMPLE AND PRACTICAL PROCEDURE FOR CONVERSION OF KETONES TO ALCOHOLS IN EXCEPTIONALLY HIGH STEREOCHEMICAL PURITY [J].

BROWN, HC ;

KRISHNAMURTHY, S .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1972, 94 (20) :7159-+

[3]

DECOURCELLES DD, 1985, J BIOL CHEM, V260, P5762

[4]

Diamond L, 1980, Adv Cancer Res, V32, P1, DOI 10.1016/S0065-230X(08)60360-7

[5] DIACYLGLYCEROLS MIMIC PHORBOL DIESTER INDUCTION OF LEUKEMIC-CELL DIFFERENTIATION [J].

EBELING, JG ;

VANDENBARK, GR ;

KUHN, LJ ;

GANONG, BR ;

BELL, RM ;

NIEDEL, JE .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1985, 82 (03) :815-819

[6] SPECIFICITY AND MECHANISM OF PROTEIN-KINASE-C ACTIVATION BY SN-1,2-DIACYLGLYCEROLS [J].

GANONG, BR ;

LOOMIS, CR ;

HANNUN, YA ;

BELL, RM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1986, 83 (05) :1184-1188

[7] ANTIPROLIFERATIVE PROPERTIES OF PHORBOL ESTER TUMOR PROMOTERS [J].

GESCHER, A .

BIOCHEMICAL PHARMACOLOGY, 1985, 34 (15) :2587-2592

[8]

GESCHER A, 1985, CANCER RES, V45, P4315

[9]

GOLDING BT, 1977, SYNTHESIS-STUTTGART, V6, P423

[10]

HARWOOD LM, COMMUNICATION

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