BURN TRAUMA INDUCES ANOREXIA AND ABERRATIONS IN CNS AMINE NEUROTRANSMITTERS

被引：13

作者：

CHANCE, WT ^{[1
]}

BERLATZKY, Y ^{[1
]}

MINNEMA, K ^{[1
]}

TROCKI, O ^{[1
]}

ALEXANDER, JW ^{[1
]}

FISCHER, JE ^{[1
]}

机构：

[1] UNIV CINCINNATI, MED CTR, DEPT SURG, 231 BETHESDA AVE, ML 558, CINCINNATI, OH 45267 USA

来源：

JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE | 1985年 / 25卷 / 06期

关键词：

D O I：

10.1097/00005373-198506000-00005

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

A 30% surface area, full-thickness, open-flame burn of guinea pigs induced significant anorexia and rapid loss of body wt. Analysis of regional brain concentrations of amine neurotransmitters suggested burn-specific elevation of serotonergic neurotransmission, reduction of dopamine metabolism and elevation of norepinephrine concentrations in brain areas thought to control feeding. Specific regional aberrations in each of these amine neurotransmitters may contribute to the anorexia associated with major thermal injury.

引用

页码：501 / 507

页数：7

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