MASSIVE ORBITAL EXTENSION OF POSTERIOR UVEAL MELANOMAS

被引：24

作者：

SHIELDS, JA

SHIELDS, CL

机构：

[1] Oncology Service, Wills Eye Hospital, Jefferson Medical College Thomas Jefferson University, Philadelphia, PA

来源：

OPHTHALMIC PLASTIC AND RECONSTRUCTIVE SURGERY | 1991年 / 7卷 / 04期

关键词：

ENUCLEATION; EXTRASCLERAL TUMOR; MASSIVE ORBITAL EXTENSION;

D O I：

10.1097/00002341-199112000-00002

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Among 2,135 consecutive patients with posterior uveal melanoma who were evaluated clinically in the Ocular Oncology Service of Wills Eye Hospital between February 1974 and December 1986, 123 (5.8%) were found to have some degree of extrascleral extension of the tumor. Ten of the 2,135 patients (0.5%) had massive orbital extension we defined as extrascleral tumor having an estimated volume exceeding 1,000 mm3. Three of these patients were characterized by orbital recurrence sometime after enucleation, whereas seven had massive orbital extension as the initial manifestation of the neoplasm with no prior history of enucleation. These cases of advanced orbital extension are presented in detail with emphasis on clinical features, diagnostic problems, pathologic findings, and follow-up observation. Based on our observations, suggestions are made regarding the diagnosis and management of advanced orbital extension of posterior uveal melanoma.

引用

页码：238 / 251

页数：14

共 22 条

[1]

Shields J.A., McDonald P.R., Improvements in the diagnosis of posterior uveal melanomas, Arch Ophthalmol, 91, pp. 259-264, (1974)

[2]

Shields J.A., Diagnosis and Management of Intraocular Tumors, pp. 194-209, (1983)

[3]

Starr H.J., Zimmerman L.E., Extrascleral extension and orbital recurrence of malignant melanomas of the ciliary body and choroid, Int Ophthalmol Clin, 2, pp. 369-385, (1962)

[4]

Shields J.A., Augsburger J.J., Brown G.C., Stephens R.F., The differential diagnosis of posterior uveal melanomas, Ophthalmology, 87, pp. 518-522, (1980)

[5]

Shields J.A., McDonald P.R., Leonard B.C., Canny C., The diagnosis of uveal melanomas in eyes with opaque media, Am J Ophthalmol, 82, pp. 95-105, (1977)

[6]

McLean I.W., Zimmerman L.E., Reappraisal of Calender's spindle A type of malignant melanoma of the choroid and ciliary body, Am J Ophthalmol, 86, pp. 557-564, (1978)

[7]

Shields J.A., Augsburger J.J., Dougherty M.J., Orbital recurrence of choroidal melanoma 20 years after enucleation, Am J Ophthalmol, 97, pp. 767-770, (1984)

[8]

Shields J.A., Augsburger J.J., Donoso L.A., Bernardino V., Portenar M., Hepatic metastasis and orbital recurrence of uveal melanoma after 42 years, Am J Ophthalmol, 100, pp. 666-668, (1985)

[9]

Shields C.L., Shields J.A., Yarian D.L., Augsburger J.J., Intracranial extension of choroidal melanoma via the optic nerve, Br J Ophthalmol, 71, pp. 172-176, (1987)

[10]

Zimmerman L.E., McLean I.W., Foster W.D., Does enucleation of the eye containing a malignant melanoma prevent or accelerate the dissemination of tumor cells?, Br J Ophthalmol, 62, pp. 420-425, (1978)

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